Research in our group focuses on the development of spectroscopic methods for molecular and materials sciences that allow to characterize complex systems that, to date, have been inaccessible with conventional analytical tools. We use the spectroscopic methods we develop to solve problems in complex systems such as enzymes, catalytic nanoparticles, pharmaceutical compounds, and live model organisms.
The group has a state-of-the-art experimental research program for the visualization of the structure and dynamics of the constituents of molecules and materials by developing new nuclear magnetic resonance spectroscopy methods.
Our research is centred around the question “How?”.
More specifically “How can we see the structure and dynamics of the invisible species that make up molecules and materials?” We use Nuclear Magnetic Resonance to find ways to do that, and our everyday tasks involve working out how the dynamics of nuclear spins can be controlled in new ways to report on systems of ever increasing complexity. Those systems range across disciplines from genetically modified nematode worms, through enzymes, to nanoparticle based catalysts and pharmaceutical formulations.
Our work is centred on new experimental observations. We invent and then implement new NMR experiments using state-of-the-art technology. Not only do we use fundamental concepts in spectroscopy and NMR spectrometers to discover structure and dynamics, but we are increasingly developing strategies that combine NMR with quantum chemical calculations (DFT) on the one hand, or sophisticated multivariate statistical data analysis on the other hand, to achieve our goals.